Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987432 | 0.82 | NOS3 (0.36) | AGXT | |
| SCHEMBL22820306 | 0.73 | CCR1 (0.39) | AGXT | |
| SCHEMBL154027 | 0.73 | AGXT (0.66) | AGXTKDM4EHPGDHSD17B10 | |
| SCHEMBL3802238 | 0.73 | AGXT (0.36) | AGXTKDM4EHPGDHSD17B10LMNA | |
| SCHEMBL11750351 | 0.70 | CCR1 (0.37) | AGXT | |
| SCHEMBL2629578 | 0.69 | NOS3 (0.33) | AGXT | |
| SCHEMBL13082509 | 0.69 | KDM4E (0.32) | KDM4E | |
| SCHEMBL21939789 | 0.68 | HPGD (0.51) | HPGDHSD17B10 | |
| SCHEMBL13030883 | 0.68 | HSP90AA1 (0.42) | AGXT | |
| SCHEMBL2110182 | 0.68 | AGXT (0.36) | AGXTKDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053161-A1 | NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS | NATIONAL TAIWAN UNIVERSITY (TW) | 2018-03-22 | — | — | WO | disclosed |