Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2629578 | 0.85 | NOS3 (0.33) | NOS3NOS2AGXT | |
| SCHEMBL3802238 | 0.85 | AGXT (0.36) | NOS3NOS2AGXT | |
| Hydrochloric Acid SCHEMBL2111722 | 0.84 | NOS3 (0.32) | NOS3NOS2AGXT | |
| SCHEMBL19987399 | 0.82 | AGXT (0.41) | AGXT | |
| SCHEMBL11750351 | 0.82 | CCR1 (0.37) | NOS3NOS2AGXTNOS1CCR1 | |
| SCHEMBL22820306 | 0.81 | CCR1 (0.39) | NOS3NOS2AGXTNOS1CCR1 | |
| SCHEMBL12319840 | 0.79 | NOS3 (0.30) | NOS3NOS2 | |
| SCHEMBL12319209 | 0.79 | NOS3 (0.38) | NOS3NOS2NOS1CCR1CCR5 | |
| SCHEMBL24039952 | 0.76 | NOS3 (0.35) | NOS3NOS2NOS1CCR1CCR5 | |
| SCHEMBL13030883 | 0.76 | HSP90AA1 (0.42) | NOS3NOS2AGXTNOS1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2021226477-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |
| WO-2018053161-A1 | NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS | NATIONAL TAIWAN UNIVERSITY (TW) | 2018-03-22 | — | — | WO | disclosed |