Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | OGA | O60502 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20437358 | 0.88 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL19275145 | 0.87 | SMN1; SMN2 (0.51) | HSD17B10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL31359263 | 0.83 | SMN1; SMN2 (0.53) | HSD17B10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL85424 | 0.83 | SMN1; SMN2 (0.53) | HSD17B10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL21028914 | 0.83 | SMN1; SMN2 (0.54) | HSD17B10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL13567871 | 0.83 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL30644691 | 0.80 | SMN1; SMN2 (0.50) | HSD17B10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL17541679 | 0.80 | SMN1; SMN2 (0.50) | HSD17B10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL17541632 | 0.80 | SMN1; SMN2 (0.54) | HSD17B10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL14587135 | 0.78 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3841093-B1 | SUCCINATE AND FUMARATE ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES USEFUL AS GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2023-06-21 | — | — | EP | disclosed |
| US-10399932-B2 | Inhibitors of indoleamine-2,3-dioxygenase for the treatment of cancer | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-09-03 | — | — | US | disclosed |
| US-20180079712-A1 | INHIBITORS OF INDOLEAMINE-2,3-DIOXYGENASE FOR THE TREATMENT OF CANCER | BRISTOL MYERS SQUIBB CO (US) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10399932-B2 | Inhibitors of indoleamine-2,3-dioxygenase for the treatment of cancer | IDO1, IDO2, INMT | HSD17B10 844/4885SMN1; SMN2 4521/4885NPC1 2350/4885 |
| US-20180079712-A1 | INHIBITORS OF INDOLEAMINE-2,3-DIOXYGENASE FOR THE TREATMENT OF CANCER | IDO1, IDO2, INMT | HSD17B10 844/4885SMN1; SMN2 4521/4885NPC1 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.