Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10101859 | 0.85 | UGT2B7 (0.41) | UGT2B7ALDH1A1GAAMAPTHPGD | |
| SCHEMBL3365122 | 0.84 | LMNA (0.47) | TSHRHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL16153835 | 0.82 | SLC6A2 (0.50) | UGT2B7TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16960369 | 0.81 | TSHR (0.37) | TSHRHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL10361088 | 0.81 | CSNK2A1 (0.39) | TSHRHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL28017111 | 0.80 | TSHR (0.44) | TSHRHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL24106174 | 0.80 | FFAR1 (0.36) | UGT2B7TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL15943228 | 0.79 | CSNK2A1 (0.53) | UGT2B7CSNK2A1KMT2ARORCMEN1 | |
| SCHEMBL661734 | 0.79 | CYP1A2 (0.51) | TSHRALDH1A1GAAMAPTHPGD | |
| SCHEMBL20032064 | 0.78 | ALDH1A1 (0.38) | TSHRHTR2AHTR2CHTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |