Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16273616 | 0.87 | PRKDC (0.34) | PRKDCMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16273742 | 0.79 | MEN1 (0.33) | PRKDCMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL17616628 | 0.78 | L3MBTL1 (0.41) | MEN1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17616600 | 0.78 | MAPT (0.34) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL16911653 | 0.78 | MEN1 (0.32) | MEN1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16273646 | 0.77 | HSP90AA1 (0.42) | MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL16627211 | 0.76 | MRGPRX4 (0.32) | MEN1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16910926 | 0.76 | NR1H4 (0.31) | — | |
| SCHEMBL16911935 | 0.76 | SLC22A12 (0.34) | GRIN1GRIN2B | |
| SCHEMBL16911126 | 0.76 | MEN1 (0.33) | MEN1ALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |