SCHEMBL16273616

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16273742	0.92	MEN1 (0.33)	PRKDCMEN1CYP1A2KMT2AALDH1A1
	SCHEMBL16911653	0.90	MEN1 (0.32)	MEN1CYP1A2KMT2AALDH1A1CYP3A4
	SCHEMBL16627211	0.89	MRGPRX4 (0.32)	MEN1CYP1A2KMT2AALDH1A1CYP3A4
	SCHEMBL19987546	0.87	PRKDC (0.33)	PRKDCMEN1CYP1A2KMT2AALDH1A1
	SCHEMBL19987549	0.86	HPGD (0.35)	MEN1CYP1A2KMT2AHPGDMRGPRX4
	SCHEMBL16910875	0.86	NR1H4 (0.35)	MEN1CYP1A2KMT2AALDH1A1CYP3A4
	SCHEMBL16273642	0.86	HPGD (0.35)	MEN1CYP1A2KMT2AALDH1A1HPGD
	SCHEMBL16273737	0.86	HPGD (0.36)	MEN1CYP1A2KMT2AALDH1A1CYP3A4
	SCHEMBL17600282	0.86	KDM4E (0.34)	PRKDCMEN1CYP1A2KMT2AALDH1A1
	SCHEMBL16273620	0.85	CXCR2 (0.36)	PRKDCMEN1CYP1A2KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.