Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 11/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18871206 | 0.84 | NR1H4 (0.35) | — | |
| SCHEMBL19987551 | 0.84 | CD274 (0.39) | CD274MRGPRX4S1PR1S1PR5FFAR4 | |
| SCHEMBL19987539 | 0.82 | CD274 (0.35) | CD274MRGPRX4S1PR1S1PR5PTGER1 | |
| SCHEMBL19987547 | 0.80 | HPGD (0.35) | CD274MRGPRX4HPGD | |
| SCHEMBL16273688 | 0.79 | MRGPRX4 (0.35) | CD274MRGPRX4S1PR1S1PR5PTGER1 | |
| SCHEMBL18831230 | 0.79 | MRGPRX4 (0.34) | CD274MRGPRX4PTGER1MMP1MMP9 | |
| SCHEMBL18831189 | 0.79 | PTGER1 (0.36) | CD274MRGPRX4S1PR1S1PR5PTGER1 | |
| SCHEMBL23506193 | 0.78 | MRGPRX4 (0.38) | CD274MRGPRX4FFAR4FFAR1HPGD | |
| SCHEMBL18831454 | 0.78 | NR1H4 (0.34) | CD274MRGPRX4MMP1MMP9MMP8 | |
| SCHEMBL18831126 | 0.77 | TP53 (0.34) | MRGPRX4MMP1MMP9MMP8HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |