SCHEMBL16273688

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16273684	0.93	MRGPRX4 (0.38)	MRGPRX4CD274HPGDS1PR1S1PR5
	SCHEMBL17600246	0.92	HPGD (0.33)	MRGPRX4CD274HPGDPLK1KDM4E
	SCHEMBL16273667	0.91	MRGPRX4 (0.35)	MRGPRX4CD274HPGDS1PR1S1PR5
	SCHEMBL16911086	0.90	MRGPRX4 (0.33)	MRGPRX4CD274HPGDKDM4EMEN1
	SCHEMBL16273679	0.90	HPGD (0.36)	MRGPRX4CD274HPGDKDM4EMEN1
	SCHEMBL16912141	0.89	MRGPRX4 (0.34)	MRGPRX4HPGDKDM4EMEN1CYP1A2
	SCHEMBL19987549	0.88	HPGD (0.35)	MRGPRX4CD274HPGDKDM4EMEN1
	SCHEMBL16911643	0.87	NR1H4 (0.38)	MRGPRX4MAPTRXFP1S1PR5PTGER1
	SCHEMBL17600083	0.86	MRGPRX4 (0.36)	MRGPRX4CD274HPGDKDM4EMEN1
	SCHEMBL16273621	0.85	MRGPRX4 (0.33)	MRGPRX4CD274HPGDKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.