Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987585 | 0.89 | HPGD (0.35) | HPGDCD274MRGPRX4ALDH1A1CYP3A4 | |
| SCHEMBL19987559 | 0.81 | MRGPRX4 (0.34) | HPGDCD274MRGPRX4ALDH1A1MAPT | |
| SCHEMBL19987560 | 0.80 | CD274 (0.35) | HPGDCD274MRGPRX4 | |
| SCHEMBL19987537 | 0.80 | KDM4E (0.33) | HPGDCD274MRGPRX4ALDH1A1CYP3A4 | |
| SCHEMBL19987551 | 0.80 | CD274 (0.39) | CD274MRGPRX4 | |
| SCHEMBL16273679 | 0.79 | HPGD (0.36) | HPGDPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18831537 | 0.78 | NR1H4 (0.37) | MRGPRX4SLC34A1ALDH1A1PKM | |
| SCHEMBL28048667 | 0.76 | MRGPRX4 (0.40) | HPGDPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19987563 | 0.76 | MRGPRX4 (0.44) | HPGDMRGPRX4ALDH1A1TP53MAPT | |
| SCHEMBL19987543 | 0.75 | MAOB (0.43) | CD274ALDH1A1MAPTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |