Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10858558 | 0.98 | SIGMAR1 (0.32) | SIGMAR1HSD11B1 | |
| SCHEMBL10943620 | 0.86 | SIGMAR1 (0.32) | SIGMAR1HSD11B1 | |
| SCHEMBL10860013 | 0.82 | — | — | |
| SCHEMBL16120990 | 0.82 | — | — | |
| SCHEMBL15337212 | 0.82 | — | — | |
| Perchlorate SCHEMBL7837149 | 0.79 | — | — | |
| SCHEMBL20390137 | 0.75 | BDKRB2 (0.33) | SIGMAR1HSD11B1BDKRB2 | |
| SCHEMBL11568926 | 0.75 | BDKRB2 (0.33) | SIGMAR1HSD11B1BDKRB2 | |
| SCHEMBL10721925 | 0.72 | SIGMAR1 (0.33) | SIGMAR1HSD11B1BDKRB2 | |
| SCHEMBL10723845 | 0.72 | SIGMAR1 (0.33) | SIGMAR1HSD11B1BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961751-B1 | 1,6- DIAZABICYCLO [3,2,1]OCTAN- 7- ONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | WOCKHARDT LTD (IN) | 2018-03-21 | — | — | EP | disclosed |