Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1998766 | 0.87 | SLC9A1 (0.39) | SLC9A1LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7903007 | 0.87 | SLC9A1 (0.39) | SLC9A1LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7913174 | 0.86 | SLC9A1 (0.38) | SLC9A1LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7916773 | 0.84 | SLC9A1 (0.37) | SLC9A1LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL926591 | 0.84 | SLC9A1 (0.39) | SLC9A1LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7902762 | 0.84 | SLC9A1 (0.37) | SLC9A1LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7911308 | 0.84 | SLC9A1 (0.37) | SLC9A1LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8132938 | 0.83 | SLC9A1 (0.36) | SLC9A1 | |
| SCHEMBL929082 | 0.81 | SLC9A1 (0.34) | SLC9A1KDM4E | |
| SCHEMBL927200 | 0.81 | SLC9A1 (0.36) | SLC9A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1849774-B1 | CYCLOHEPTA(b)PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING SAME | TOA EIYO LTD (JP) | 2011-06-29 | — | — | EP | claimed |