Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910351 | 0.97 | SLC9A1 (0.35) | SLC9A1KDM4EACHESMN1; SMN2ALDH1A1 | |
| SCHEMBL7903007 | 0.85 | SLC9A1 (0.39) | SLC9A1KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1998766 | 0.85 | SLC9A1 (0.39) | SLC9A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL7913174 | 0.84 | SLC9A1 (0.38) | SLC9A1KDM4EACHESMN1; SMN2ALDH1A1 | |
| SCHEMBL1998764 | 0.84 | SLC9A1 (0.38) | SLC9A1KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL926591 | 0.83 | SLC9A1 (0.39) | SLC9A1KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7902762 | 0.82 | SLC9A1 (0.37) | SLC9A1KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7911308 | 0.82 | SLC9A1 (0.37) | SLC9A1KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8132938 | 0.81 | SLC9A1 (0.36) | SLC9A1CNR1CNR2 | |
| SCHEMBL2006215 | 0.80 | SLC9A1 (0.32) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |