Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.64 |
| ▸ | RXRB | P28702 | 3/20 | 0.64 |
| ▸ | ACHE | P22303 | 3/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179538 | 0.98 | RXRA (0.66) | RXRARXRBACHENR1H4NR4A1 | |
| SCHEMBL29466781 | 0.86 | RXRA (0.56) | RXRARXRBACHENR4A1NR4A2 | |
| SCHEMBL1041916 | 0.86 | RXRA (0.56) | RXRARXRBACHENR4A1NR4A2 | |
| SCHEMBL29486118 | 0.84 | RXRA (0.54) | RXRARXRBACHENR4A1NR4A2 | |
| SCHEMBL2637669 | 0.84 | RXRA (0.54) | RXRARXRBACHENR4A1NR4A2 | |
| SCHEMBL28374573 | 0.83 | NR1H4 (0.59) | RXRARXRBACHENR1H4NR4A1 | |
| SCHEMBL3684740 | 0.82 | ATM (0.63) | RXRARXRBACHENR1H4SRD5A2 | |
| SCHEMBL16019040 | 0.82 | ACHE (0.64) | RXRARXRBACHENR1H4HDAC8 | |
| SCHEMBL3932481 | 0.82 | SRD5A2 (0.57) | RXRARXRBACHENR4A2MRGPRX4 | |
| SCHEMBL12065518 | 0.82 | RXRA (0.53) | RXRARXRBACHENR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10563041-B2 | Rubber composition for coating steel cord and tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2020-02-18 | — | — | US | disclosed |
| EP-3299414-B1 | RUBBER COMPOSITION FOR COATING STEEL CORD AND TIRE | SUMITOMO RUBBER IND (JP) | 2019-06-19 | — | — | EP | disclosed |
| US-20180086897-A1 | RUBBER COMPOSITION FOR COATING STEEL CORD AND TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2018-03-29 | — | — | US | disclosed |
| EP-3299414-A1 | RUBBER COMPOSITION FOR COATING STEEL CORD AND TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2018-03-28 | — | — | EP | disclosed |