SCHEMBL179538

SCHEMBL179538

CC(C)(C)c1cccc(C(=O)O)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 3/20 0.66
RXRB P28702 3/20 0.66
ACHE P22303 3/20 0.65
NR1H4 Q96RI1 2/20 0.54
NR4A1 P22736 1/20 0.54
NR4A2 P43354 1/20 0.54
NR4A3 Q92570 1/20 0.54
MRGPRX4 Q96LA9 1/20 0.54
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA6 P23280 1/20 0.52
CA9 Q16790 1/20 0.52
SRD5A2 P31213 2/20 0.52
RXRG P48443 1/20 0.52
HDAC8 Q9BY41 2/20 0.51
HDAC6 Q9UBN7 1/20 0.51
HDAC4 P56524 1/20 0.50
HDAC2 Q92769 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19987946 0.98 RXRA (0.64) RXRARXRBACHENR1H4NR4A1
SCHEMBL1041916 0.88 RXRA (0.56) RXRARXRBACHENR4A1NR4A2
SCHEMBL29466781 0.88 RXRA (0.56) RXRARXRBACHENR4A1NR4A2
SCHEMBL2637669 0.86 RXRA (0.54) RXRARXRBACHENR4A1NR4A2
SCHEMBL29486118 0.86 RXRA (0.54) RXRARXRBACHENR4A1NR4A2
SCHEMBL28374573 0.84 NR1H4 (0.59) RXRARXRBACHENR1H4NR4A1
SCHEMBL3932481 0.84 SRD5A2 (0.57) RXRARXRBACHENR4A2MRGPRX4
SCHEMBL29408183 0.84 SRD5A2 (0.57) RXRARXRBACHENR4A2MRGPRX4
SCHEMBL12065518 0.84 RXRA (0.53) RXRARXRBACHENR4A1NR4A2
SCHEMBL1635891 0.84 ESR1 (0.55) RXRARXRBACHENR1H4NR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 547 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118459334-A Method for separating p-tert-butylbenzoic acid and m-tert-butylbenzoic acid isomers 德清乾精新材料科技有限公司 2024-08-09 CN claimed
CN-112852014-B Asymmetric organic aromatic ligand metal salt nucleating agent and preparation method and application thereof 华东理工大学 2022-03-15 CN claimed
CN-112852014-A Asymmetric organic aromatic ligand metal salt nucleating agent and preparation method and application thereof 华东理工大学 2021-05-28 CN claimed
CN-109836618-B Modification method of aluminum oxide 中国石油天然气股份有限公司 2021-03-30 CN claimed
EP-4745191-A1 POLYVINYL CHLORIDE-BASED RESIN COMPOSITION, AND FILM PRODUCED THEREFROM Riken Technos Corporation (JP) 2026-05-20 EP disclosed
CN-122037013-A Catalytic component, catalyst for olefin prepolymerization or polymerization, and method for olefin prepolymerization or polymerization 中国石油化工股份有限公司 2026-05-15 CN disclosed
US-20250305210-A1 FIBER-TREATING AGENT KAO CORPORATION (JP) 2025-10-02 US disclosed
US-12383560-B2 Compounds and uses thereof FOGHORN THERAPEUTICS INC. (US) 2025-08-12 US disclosed
US-12286509-B2 Radiation curable compositions ALLNEX BELGIUM S.A. (BE) 2025-04-29 US disclosed
WO-2025079658-A1 FIBER TREATMENT AGENT 花王株式会社 2025-04-17 WO disclosed
EP-4528021-A1 FIBER-TREATING AGENT Kao Corporation (JP) 2025-03-26 EP disclosed
WO-2025018141-A1 POLYVINYL CHLORIDE-BASED RESIN COMPOSITION, AND FILM PRODUCED THEREFROM リケンテクノス株式会社 2025-01-23 WO disclosed
EP-0507576-A1 Polypropylene-based resin compositions TOSOH CORPORATION (JP) 1992-10-07 EP disclosed
US-5153342-A Esterification of 2,2,4-trimethyl-1,3-pentanediol with (alkyl) benzoic acids using basic catalysts HULS AMERICA INC. (US) 1992-10-06 US disclosed
US-5039728-A Floor and wall coverings; vinly chloride homo- and copolymers HULS AMERICA INC. (US) 1991-08-13 US disclosed
US-5006585-A Hydroxy ester compounds, stain resistance, vinyl chloride polymers HULS AMERICA INC. (US) 1991-04-09 US disclosed
EP-0416822-A2 Stain-resistant plasticizer compositions and method of making same VELSICOL CHEMICAL CORPORATION (US) 1991-03-13 EP disclosed
US-4332701-A FOR COATINGS DUNLOP LIMITED (GB) 1982-06-01 US disclosed
US-4131677-A Anti-inflammatory oxazolo [5,4-b]pyridines MERCK & CO., INC. (US) 1978-12-26 US disclosed
US-4038396-A ANTIPYRETICS, ANALGESICS MERCK & CO., INC. (US) 1977-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12383560-B2 Compounds and uses thereof VHL, CLN6, TFEB RXRA 163/4885RXRB 103/4885ACHE 4721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.