Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28735867 | 0.87 | EPHX2 (0.34) | EPHX2GFER | |
| SCHEMBL29148112 | 0.86 | EPHX2 (0.42) | EPHX2GFERDAOADORA2AADORA2B | |
| SCHEMBL28302805 | 0.81 | EPHX2 (0.39) | EPHX2GFERDAOCYP3A4MAPK1 | |
| SCHEMBL11294427 | 0.80 | EPHX2 (0.38) | EPHX2GFERDAOCYP3A4MAPK1 | |
| SCHEMBL6421931 | 0.78 | KDM1A (0.39) | EPHX2GFERADORA2AADORA2BMAPK1 | |
| SCHEMBL11293666 | 0.75 | KDM4E (0.36) | EPHX2GFERDAOALDH1A1NPSR1 | |
| SCHEMBL538937 | 0.74 | PMP22 (0.51) | ADORA2AADORA2BCYP3A4MAPK1PMP22 | |
| SCHEMBL9151741 | 0.73 | — | — | |
| SCHEMBL5085666 | 0.73 | MAPK10 (0.44) | MAPK1ALDH1A1NPSR1MAPTHPGD | |
| SCHEMBL8570025 | 0.73 | EPHX2 (0.33) | EPHX2GFERALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299010-A1 | ORAL DOSAGE FORM | LTS Lohmann Therapie-Systeme AG (DE) | 2018-03-28 | — | — | EP | disclosed |