Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 3/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944697 | 0.91 | MAPT (0.37) | KDM1AHPGDCYP2C9EPHX2SMN1; SMN2 | |
| SCHEMBL6948264 | 0.89 | EPHX2 (0.37) | KDM1AHPGDCYP2C9EPHX2SMN1; SMN2 | |
| SCHEMBL5085666 | 0.88 | MAPK10 (0.44) | HPGDCYP2C9SMN1; SMN2MAPTMAPK10 | |
| SCHEMBL11294427 | 0.87 | EPHX2 (0.38) | KDM1AHPGDCYP2C9EPHX2GFER | |
| SCHEMBL8952242 | 0.82 | EPHX2 (0.33) | KDM1AHPGDEPHX2MAPTMEN1 | |
| SCHEMBL8803670 | 0.81 | TK1 (0.43) | HPGDSMN1; SMN2MAPTMAPK10MEN1 | |
| SCHEMBL11293666 | 0.81 | KDM4E (0.36) | HPGDEPHX2MAPTKDM4EGFER | |
| SCHEMBL8952545 | 0.81 | EPHX2 (0.33) | EPHX2MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL8952586 | 0.81 | KDM4E (0.36) | HPGDCYP2C9EPHX2MAPTKDM4E | |
| SCHEMBL8952620 | 0.81 | KDM4E (0.36) | HPGDCYP2C9EPHX2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558291-A2 | rAAV-VECTORED RIBOZYME COMPOSITIONS AND METHODS FOR THE TREATMENT OF RETINAL DISEASES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2005-08-03 | — | — | EP | disclosed |
| WO-2002088320-A2 | rAAV-VECTORED RIBOZYME COMPOSITIONS AND METHODS FOR THE TREATMENT OF RETINAL DISEASES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. (US) | 2002-11-07 | — | — | WO | disclosed |