Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | XBP1 | P17861 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944697 | 0.94 | MAPT (0.37) | MAPK10KMT2AMEN1MAPK1TSHR | |
| SCHEMBL8803670 | 0.92 | TK1 (0.43) | MAPK10KMT2AMEN1MAPK1TSHR | |
| SCHEMBL9392011 | 0.91 | KMT2A (0.38) | MAPK10KMT2AMEN1MAPK1TSHR | |
| SCHEMBL8802577 | 0.90 | MAPK10 (0.38) | MAPK10KMT2AMEN1MAPK1TSHR | |
| SCHEMBL6421931 | 0.88 | KDM1A (0.39) | MAPK10KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL8952545 | 0.87 | EPHX2 (0.33) | MAPK10KMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL8952620 | 0.87 | KDM4E (0.36) | MAPK10KMT2AMEN1MAPK1HPGD | |
| SCHEMBL8952586 | 0.87 | KDM4E (0.36) | MAPK10KMT2AMEN1MAPK1HPGD | |
| SCHEMBL8952638 | 0.87 | KDM4E (0.36) | MAPK10KMT2AMEN1MAPK1HPGD | |
| SCHEMBL8952508 | 0.87 | KDM4E (0.36) | MAPK10KMT2AMEN1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111787920-A | Pharmaceutical composition for controlling and/or reducing myopia progression | 华柏恩视觉研究中心有限公司 | 2020-10-16 | — | — | CN | disclosed |
| EP-3703691-A1 | PHARMACEUTICAL COMPOSITIONS FOR CONTROLLING AND/OR REDUCING THE PROGRESSION OF MYOPIA | Brien Holden Vision Institute Limited (AU) | 2020-09-09 | — | — | EP | disclosed |
| WO-2008033754-A2 | XANTHINE DERIVATIVES IN METHODS AND COMPOSITIONS FOR THE TREATMENT OF VASCULAR DEPRESSION | DUKE UNIVERSITY (US) | 2008-03-20 | — | — | WO | disclosed |
| EP-1322184-A2 | BEVERAGE COMPOSITIONS COMPRISING ARABINOGALACTAN AND DEFINED VITAMINS | THE PROCTER & GAMBLE COMPANY (US) | 2003-07-02 | — | — | EP | disclosed |
| EP-1322185-A2 | BEVERAGE COMPOSITIONS COMPRISING ARABINOGALACTAN AND MINERAL SUPPLEMENT | THE PROCTER & GAMBLE COMPANY (US) | 2003-07-02 | — | — | EP | disclosed |
| EP-1289532-A2 | LOW CARBOHYDRATE COMPOSITIONS, KITS THEREOF, AND METHODS OF USE | The Procter & Gamble Company (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-1196050-A1 | COMPOSITIONS, KITS, AND METHODS FOR PROVIDING AND MAINTAINING ENERGY AND MENTAL ALERTNESS | THE PROCTER & GAMBLE COMPANY (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2002026055-A2 | BEVERAGE COMPOSITIONS COMPRISING ARABINOGALACTAN AND DEFINED VITAMINS | THE PROCTER & GAMBLE COMPANY (US) | 2002-04-04 | — | — | WO | disclosed |
| WO-2002026053-A2 | BEVERAGE COMPOSITIONS COMPRISING ARABINOGALACTAN AND MINERAL SUPPLEMENT | THE PROCTER & GAMBLE COMPANY (US) | 2002-04-04 | — | — | WO | disclosed |
| WO-2001093831-A2 | LOW CARBOHYDRATE COMPOSITIONS, KITS THEREOF, AND METHODS OF USE | THE PROCTER & GAMBLE COMPANY (US) | 2001-12-13 | — | — | WO | disclosed |
| WO-2001005253-A1 | COMPOSITIONS, KITS, AND METHODS FOR PROVIDING AND MAINTAINING ENERGY AND MENTAL ALERTNESS | THE PROCTER & GAMBLE COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |
| WO-1998030900-A2 | SCREENING METHOD FOR COMPOUNDS ACTIVE IN TREATING MYOPIA AND HYPERMETROPIA | KLAUS TRIER APS (DK) | 1998-07-16 | — | — | WO | disclosed |
| CN-1085557-A | The enantiomorph hydroxylated xanthine compounds | CELL THERAPEUTICS INC (US) | 1994-04-20 | — | — | CN | disclosed |
| WO-1992007585-A1 | THE USE OF ANTIBODIES TO TNF OR FRAGMENTS DERIVED THEREOF AND XANTHINE DERIVATIVES FOR COMBINATION THERAPY AND COMPOSITIONS THEREFOR | CELLTECH LIMITED (GB) | 1992-05-14 | — | — | WO | disclosed |
| EP-0252487-B1 | PACKAGE CONTAINING DRUG COMBINATIONS FOR SUCCESSIVE ADMINISTRATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-08 | — | — | EP | disclosed |
| EP-0252487-A2 | Package containing drug combinations for successive administration | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |
| EP-0208962-A2 | Combination preparations from thrombocyte aggregation inhibitors, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-01-21 | — | — | EP | disclosed |