SCHEMBL19988063

SCHEMBL19988063

CC(C(=O)O)=C(NC(N)=O)NC(N)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.50
LMNA P02545 3/20 0.35
BLM P54132 2/20 0.35
PMP22 Q01453 2/20 0.35
ALOX15 P16050 1/20 0.35
TAS2R38 P59533 1/20 0.35
LDHA P00338 1/20 0.33
LDHB P07195 1/20 0.33
TSHR P16473 2/20 0.32
NFKB1 P19838 2/20 0.32
CYP1A2 P05177 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
THPO P40225 1/20 0.32
CA2 P00918 1/20 0.32
CYP3A4 P08684 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
KDM5B Q9UGL1 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5315913 0.79 CRBN (0.50) CRBNLMNABLMPMP22ALOX15
SCHEMBL472247 0.77 CRBN (0.42) CRBNALOX15TAS2R38FFAR3
SCHEMBL9013440 0.77 CRBN (0.42) CRBNALOX15TAS2R38FFAR3
SCHEMBL30958928 0.75 CRBN (0.46) CRBNLMNABLMPMP22ALOX15
Acetic Acid SCHEMBL28316382 0.74 CRBN (0.65) CRBNLMNABLMPMP22ALOX15
SCHEMBL2189435 0.73 CRBN (0.39) CRBNALOX15TSHRFFAR3
Hydrogen Peroxide SCHEMBL4232421 0.69
SCHEMBL751801 0.67
SCHEMBL1704654 0.67
SCHEMBL20237254 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2928934-B1 STABLE AQUEOUS DISPERSION OF PARTICLE POLYMERS CONTAINING STRUCTURAL UNITS OF 2-(METHACRYLOYLOXY)ETHYL PHOSPHONIC ACID AND COMPOSITES THEREOF ROHM & HAAS (US) 2018-10-24 EP claimed
EP-3034524-B1 POLYVINYL ACETATE LATEX ROHM & HAAS (US) 2018-03-28 EP claimed