SCHEMBL5315913

SCHEMBL5315913

C/C(NC(N)=O)=C(/C)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.50
LMNA P02545 3/20 0.35
BLM P54132 2/20 0.35
PMP22 Q01453 2/20 0.35
ALOX15 P16050 1/20 0.35
TAS2R38 P59533 1/20 0.35
LDHA P00338 1/20 0.33
LDHB P07195 1/20 0.33
TSHR P16473 2/20 0.32
NFKB1 P19838 2/20 0.32
CYP1A2 P05177 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
THPO P40225 1/20 0.32
CA2 P00918 1/20 0.32
CYP3A4 P08684 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
KDM5B Q9UGL1 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19988063 0.79 CRBN (0.50) CRBNLMNABLMPMP22ALOX15
SCHEMBL28564768 0.78 CRBN (0.41) CRBNTAS2R38NFKB1CA2KDM5B
SCHEMBL10791078 0.78 KDM5B (0.33) KDM5BFFAR3LCKFYN
SCHEMBL30958928 0.75 CRBN (0.46) CRBNLMNABLMPMP22ALOX15
SCHEMBL21623667 0.75
Acetic Acid SCHEMBL28316382 0.74 CRBN (0.65) CRBNLMNABLMPMP22ALOX15
SCHEMBL20217891 0.73 CRBN (0.44) CRBNLMNABLMPMP22ALOX15
SCHEMBL472247 0.72 CRBN (0.42) CRBNALOX15TAS2R38FFAR3
SCHEMBL9013440 0.72 CRBN (0.42) CRBNALOX15TAS2R38FFAR3
SCHEMBL24394998 0.70 MEN1 (0.36) LMNAFFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006122923-A1 AROMATIC HETEROCYCLES AS STABILIZERS OF POLYMERIZABLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2006-11-23 WO claimed
EP-1670877-A1 RADICAL INTERCEPTORS AS STABILIZERS OF POLYMERIZABLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2006-06-21 EP claimed
WO-2005030907-A1 RADICAL INTERCEPTORS AS STABILIZERS OF POLYMERIZABLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2005-04-07 WO claimed
EP-1518916-A1 Scavenger of free radicals as stabilizers of polymerisable compounds BASF AKTIENGESELLSCHAFT (DE) 2005-03-30 EP claimed
EP-3145964-B1 ADHESION PROMOTER FOR AQUEOUS COATING COMPOSITIONS BASF COATINGS GMBH (DE) 2018-07-18 EP disclosed
EP-3145964-A1 ADHESION PROMOTER FOR AQUEOUS COATING COMPOSITIONS BASF Coatings GmbH (DE) 2017-03-29 EP disclosed
WO-2015176854-A1 ADHESION PROMOTER FOR AQUEOUS COATING COMPOSITIONS BASF COATINGS GMBH (DE) 2015-11-26 WO disclosed
WO-2007063031-A2 STABILIZED POLYMERIZABLE MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2007-06-07 WO disclosed
WO-2006122923-A1 AROMATIC HETEROCYCLES AS STABILIZERS OF POLYMERIZABLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2006-11-23 WO disclosed
EP-1670877-A1 RADICAL INTERCEPTORS AS STABILIZERS OF POLYMERIZABLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2006-06-21 EP disclosed
WO-2005030907-A1 RADICAL INTERCEPTORS AS STABILIZERS OF POLYMERIZABLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2005-04-07 WO disclosed
EP-1518916-A1 Scavenger of free radicals as stabilizers of polymerisable compounds BASF AKTIENGESELLSCHAFT (DE) 2005-03-30 EP disclosed