Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dp001. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR known ✓ | P11473 | 6/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dp001 SCHEMBL12961887 | 1.00 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL29645040 | 1.00 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL15371114 | 1.00 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL15371106 | 1.00 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL18470321 | 1.00 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL12932256 | 1.00 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL8303273 | 1.00 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL10307542 | 1.00 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL21206294 | 1.00 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL12332637 | 1.00 | VDR (0.81) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681311-B1 | ACTIVE VITAMIN D OR ANALOGS THEREOF FOR USE IN IN VITRO FERTILIZATION | RIGSHOSPITALET COPENHAGEN UNIV HOSPITAL (DK) | 2018-03-28 | — | — | EP | disclosed |