Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 12/20 | 0.79 |
| ▸ | MAPT | P10636 | 2/20 | 0.79 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.79 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.79 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.79 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.79 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.79 |
| ▸ | GC | P02774 | 1/20 | 0.79 |
| ▸ | PGR | P06401 | 1/20 | 0.79 |
| ▸ | RXRA | P19793 | 1/20 | 0.79 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.79 |
| ▸ | CNR1 | P21554 | 1/20 | 0.79 |
| ▸ | HTR2C | P28335 | 1/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.79 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.79 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.79 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046820 | 1.00 | VDR (0.79) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL11214356 | 1.00 | VDR (0.79) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL16317485 | 1.00 | VDR (0.79) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL19988215 | 1.00 | VDR (0.79) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL7139484 | 1.00 | VDR (0.79) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL16357773 | 1.00 | VDR (0.79) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL7139481 | 1.00 | VDR (0.79) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL9626954 | 0.92 | VDR (0.71) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL3679281 | 0.91 | VDR (0.83) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL14373325 | 0.91 | VDR (0.82) | VDRMAPTADORA3SLC6A2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065592-B1 | COCRYSTALS OF STEROID AND SECOSTEROID COMPOUNDS AND COMPOSITIONS COMPRISING THEM | CENTER FOR INTELLIGENT RES IN CRYSTAL ENGINEERING S L (ES) | 2024-01-10 | — | — | EP | claimed |
| US-20230001012-A1 | COCRYSTALS OF STEROID AND SECOSTEROID COMPOUNDS AND COMPOSITIONS COMPRISING THEM | CENTER FOR INTELLIGENT RESEARCH IN CRYSTAL ENGINEERING, S.L. (ES) | 2023-01-05 | — | — | US | claimed |
| EP-4065592-B1 | COCRYSTALS OF STEROID AND SECOSTEROID COMPOUNDS AND COMPOSITIONS COMPRISING THEM | CENTER FOR INTELLIGENT RES IN CRYSTAL ENGINEERING S L (ES) | 2024-01-10 | — | — | EP | disclosed |
| US-20230001012-A1 | COCRYSTALS OF STEROID AND SECOSTEROID COMPOUNDS AND COMPOSITIONS COMPRISING THEM | CENTER FOR INTELLIGENT RESEARCH IN CRYSTAL ENGINEERING, S.L. (ES) | 2023-01-05 | — | — | US | disclosed |
| EP-2681311-B1 | ACTIVE VITAMIN D OR ANALOGS THEREOF FOR USE IN IN VITRO FERTILIZATION | RIGSHOSPITALET COPENHAGEN UNIV HOSPITAL (DK) | 2018-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230001012-A1 | COCRYSTALS OF STEROID AND SECOSTEROID COMPOUNDS AND COMPOSITIONS COMPRISING THEM | HSD3B1, HSD3B2, NR3C2 | VDR 234/4885MAPT 3460/4885ADORA3 3162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.