SCHEMBL19989634

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20025509	0.85	KDM4E (0.41)	KDM4EMAPTALDH1A1MMP2MMP3
	SCHEMBL19989719	0.85	HTR1A (0.38)	HTR1ADRD4KMT2AMEN1SIGMAR1
	SCHEMBL19989625	0.84	HTR1A (0.37)	KDM4EMAPTALDH1A1GAAHTR1A
	SCHEMBL19989648	0.81	SLC6A2 (0.54)	KDM4EMAPTMMP2MMP3SIGMAR1
	SCHEMBL19989662	0.81	DRD4 (0.35)	HTR1ADRD4KMT2AMEN1
	SCHEMBL11899084	0.79	SLC6A2 (0.59)	SLC6A2MMP12MMP13
	SCHEMBL19989629	0.79	MEN1 (0.35)	KDM4EMAPTALDH1A1HTR1ADRD4
	SCHEMBL19989710	0.79	KDM4E (0.49)	KDM4EMAPTALDH1A1MMP2MMP3
	SCHEMBL19989682	0.79	DRD4 (0.34)	KDM4EMAPTALDH1A1HTR1ADRD4
	SCHEMBL19989695	0.78	KDM4E (0.50)	KDM4EMAPTALDH1A1MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.