SCHEMBL1998994

SCHEMBL1998994

CCCCNCCC[Si](OC)(OC)OC.CO[Si](CCCNCCC[Si](OC)(OC)OC)(OC)OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
TSHR P16473 2/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP2C19 P33261 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
GLA P06280 1/20 0.35
ADH1B P00325 1/20 0.34
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34
ADH7 P40394 1/20 0.34
ACHE P22303 5/20 0.33
HRH4 Q9H3N8 2/20 0.33
HRH3 Q9Y5N1 2/20 0.33
PAOX Q6QHF9 1/20 0.33
CYP1A2 P05177 1/20 0.33
EPHX1 P07099 1/20 0.33
TLR8 Q9NR97 1/20 0.33
TLR7 Q9NYK1 1/20 0.33
S1PR2 O95136 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56471 1.00 LMNA (0.47) LMNATSHRALDH1A1CYP2C19KMT2A
SCHEMBL1411794 0.98 LMNA (0.46) LMNATSHRALDH1A1CYP2C19KMT2A
Hydrochloric Acid SCHEMBL1567031 0.98 LMNA (0.46) LMNATSHRALDH1A1CYP2C19KMT2A
SCHEMBL13240314 0.98 LMNA (0.46) LMNATSHRALDH1A1CYP2C19KMT2A
SCHEMBL22344106 0.94 LMNA (0.43) LMNATSHRALDH1A1CYP2C19KMT2A
SCHEMBL15360412 0.93 TSHR (0.50) LMNATSHRALDH1A1CYP2C19KMT2A
SCHEMBL88311 0.93 TSHR (0.56) LMNATSHRALDH1A1CYP2C19ADH1B
SCHEMBL27041450 0.92 LMNA (0.42) LMNATSHRALDH1A1CYP2C19KMT2A
SCHEMBL7044621 0.91 ALDH1A1 (0.54) LMNATSHRALDH1A1ADH1BADH1C
SCHEMBL13146321 0.91 ALDH1A1 (0.54) LMNATSHRALDH1A1ADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3688052-B1 ACTIVATOR FOR ACCELERATED ADHESIVE COMPOSITION SIKA TECH AG (CH) 2021-11-10 EP disclosed
EP-3688052-A1 ACTIVATOR FOR ACCELERATED ADHESION DEVELOPMENT Sika Technology AG (CH) 2020-08-05 EP disclosed
WO-2019063353-A1 ACTIVATOR FOR ACCELERATED ADHESION DEVELOPMENT SIKA TECHNOLOGY AG (CH) 2019-04-04 WO disclosed
EP-3287276-A1 REACTIVE POLYOLEFIN HOT-MELT ADHESIVE WITH LOWER REACTIVATION TEMPERATURE AND USE THEREOF IN DEEP DRAW VACUUM LAMINATION SIKA TECHNOLOGY AG (CH) 2018-02-28 EP disclosed
US-8865822-B2 Hot melt adhesive compositions having good adhesion on both polar and nonpolar substrates SIKA TECHNOLOGY AG (CH) 2014-10-21 US disclosed
US-20120315491-A1 HOT MELT ADHESIVE COMPOSITIONS HAVING GOOD ADHESION ON BOTH POLAR AND NONPOLAR SUBSTRATES SIKA TECHNOLOGY AG (CH) 2012-12-13 US disclosed
EP-2336261-B1 Hot melt adhesive compounds with good adhesion on polar and apolar substrates SIKA TECHNOLOGY AG (CH) 2012-04-25 EP disclosed
EP-2336261-A1 Hot melt adhesive compounds with good adhesion on polar and apolar substrates Sika Technology AG (CH) 2011-06-22 EP disclosed