SCHEMBL1999057

SCHEMBL1999057

CCCCC(=O)Oc1ccc(F)c(F)c1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.45
TP53 P04637 1/20 0.45
KMT2A Q03164 6/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 1/20 0.44
RECQL P46063 1/20 0.44
CA2 P00918 3/20 0.43
ALDH1A1 P00352 2/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
HSD17B10 Q99714 1/20 0.43
BCL9 O00512 1/20 0.42
CTNNB1 P35222 1/20 0.42
HTR1A P08908 1/20 0.42
HTR1B P28222 1/20 0.42
GLA P06280 1/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9223403 0.94 KMT2A (0.52) KMT2ASMN1; SMN2MEN1CA2ALDH1A1
SCHEMBL1996155 0.90 BCL9 (0.51) MAPTKMT2AKDM4ECA2ALDH1A1
SCHEMBL16582465 0.90 KMT2A (0.47) MAPTKMT2ASMN1; SMN2KDM4EMEN1
SCHEMBL27539609 0.88 CA2 (0.44) MAPTTP53KMT2ASMN1; SMN2KDM4E
SCHEMBL13274098 0.86 CA2 (0.44) MAPTTP53KMT2ASMN1; SMN2KDM4E
SCHEMBL1717364 0.86 HPGD (0.46) MAPTTP53KMT2ASMN1; SMN2KDM4E
SCHEMBL15185191 0.84 ELANE (0.39) MAPTTP53KMT2ASMN1; SMN2KDM4E
SCHEMBL1997102 0.83 KMT2A (0.43) MAPTTP53KMT2ASMN1; SMN2KDM4E
SCHEMBL1787665 0.83 KMT2A (0.53) MAPTKMT2ASMN1; SMN2KDM4ERECQL
SCHEMBL16582459 0.83 KMT2A (0.45) MAPTKMT2ASMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
CN-116209433-A Small molecule albumin binding agents 俄勒冈健康科学大学 2023-06-02 CN disclosed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
CN-102186921-B Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2014-01-15 CN disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
CN-102186921-A Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2011-09-14 CN disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed