Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1999057 | 0.86 | MAPT (0.45) | MAPTTP53RECQLHTTKMT2A | |
| SCHEMBL9188821 | 0.84 | CHRNA3 (0.43) | HPGDPPARGPPARARECQLHTT | |
| SCHEMBL9188827 | 0.84 | CHRNA3 (0.43) | HPGDPPARGPPARARECQLHTT | |
| SCHEMBL31506663 | 0.83 | PPARG (0.46) | MAPTPPARGPPARAHTTCHRNA3 | |
| SCHEMBL9185233 | 0.83 | CHRNA3 (0.42) | HPGDCHRNA3KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9185226 | 0.83 | CHRNA3 (0.42) | HPGDCHRNA3KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL13274098 | 0.82 | CA2 (0.44) | MAPTTP53RECQLHTTKMT2A | |
| SCHEMBL9190127 | 0.82 | CHRNA3 (0.42) | HPGDCHRNA3KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9190134 | 0.82 | CHRNA3 (0.42) | HPGDCHRNA3KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9186577 | 0.82 | CHRNA3 (0.42) | HPGDCHRNA3KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992618-B1 | POLYCYCLIC CINNAMIDE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2012-01-18 | — | — | EP | disclosed |