Biphenyl

Biphenyl

SCHEMBL19990802

C=CC=C.CC.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
SLC22A2 O15244 1/20 0.43
SLC22A1 O15245 1/20 0.43
SLC22A3 O75751 1/20 0.43
SLC6A4 P31645 1/20 0.43
TSHR P16473 1/20 0.43
TAAR1 Q96RJ0 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
MAPK1 P28482 2/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NOTUM Q6P988 1/20 0.41
MMP3 P08254 1/20 0.41
BCL2L1 Q07817 1/20 0.41
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL322601 0.94 ALDH1A1 (0.64) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL2932531 0.90 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL1712848 0.90 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL27495887 0.90 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL27523826 0.88 ALDH1A1 (0.50) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL664141 0.84 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL653702 0.83 ALDH1A1 (0.82) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL5599687 0.81 ALDH1A1 (0.56) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL27652579 0.81 ALDH1A1 (0.56) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL896273 0.80 ALDH1A1 (0.41) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10000599-B2 Phosphorus-containing vinyl polyphenylene ether, resin composition comprising phosphorus-containing vinyl polyphenylene ether and product thereof Elite Material Co., Ltd. (TW) 2018-06-19 US disclosed
US-20180086870-A1 PHOSPHORUS-CONTAINING VINYL POLYPHENYLENE ETHER, RESIN COMPOSITION COMPRISING PHOSPHORUS-CONTAINING VINYL POLYPHENYLENE ETHER AND PRODUCT THEREOF Elite Material Co., Ltd. (TW) 2018-03-29 US disclosed