Biphenyl

Biphenyl

SCHEMBL664141

C=CC.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
SLC22A2 O15244 1/20 0.46
SLC22A1 O15245 1/20 0.46
SLC22A3 O75751 1/20 0.46
SLC6A4 P31645 1/20 0.46
TSHR P16473 1/20 0.45
CYP1A2 P05177 2/20 0.43
MAPT P10636 2/20 0.43
CYP3A4 P08684 2/20 0.43
TAAR1 Q96RJ0 2/20 0.43
MAPK1 P28482 2/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NOTUM Q6P988 1/20 0.43
MMP3 P08254 1/20 0.43
BCL2L1 Q07817 1/20 0.43
BRD4 O60885 1/20 0.41
BRD2 P25440 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL19990802 0.84 ALDH1A1 (0.56) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL28799578 0.83 ALDH1A1 (0.64) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL322601 0.83 ALDH1A1 (0.64) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Propene SCHEMBL60604 0.82
Biphenyl SCHEMBL2948084 0.80 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL2932531 0.80 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL27472529 0.80 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL1712848 0.80 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL27495887 0.80 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL28220204 0.80 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271578-A Polymer with phosphonic acid structure in side chain, synthesis method and application thereof in high-temperature proton exchange membrane fuel cell 中国科学院山西煤炭化学研究所 2024-07-02 CN claimed
CN-112680035-B Artistic paint and preparation method thereof 广东博智林机器人有限公司 2021-06-22 CN claimed
CN-108276376-B Novel diphenylpropenes derivative, preparation method thereof and pharmaceutical composition 北京理工大学 2020-06-05 CN claimed
CN-105330569-A Preparation method of (R)-2-(N-tertbutyloxycarbonylamino)biphenylpropanol TONGJING OPTOELECTRONICS TECHNOLOGY CO LTD 2016-02-17 CN claimed
CN-103254027-A Method for preparing 1,2-diphenyl propylene compound SINOCHEM CORP 2013-08-21 CN claimed
CN-1744892-A Breast cancer resistance protein (BCRP) inhibitor YAKULT HONSHA KK (JP) 2006-03-08 CN claimed
CN-1513027-A Styrenic thermoplastic resin composition LG化学株式会社 2004-07-14 CN claimed
CN-118271578-A Polymer with phosphonic acid structure in side chain, synthesis method and application thereof in high-temperature proton exchange membrane fuel cell 中国科学院山西煤炭化学研究所 2024-07-02 CN disclosed
CN-118165198-A Application of phosphonated hydrocarbon polymer with large steric hindrance effect as binder in high-temperature proton exchange membrane fuel cell 中国科学院山西煤炭化学研究所 2024-06-11 CN disclosed
CN-115769820-A Nanometer dry suspending agent containing flumorph and ametoctradin and preparation method thereof 惠州市银农科技股份有限公司 2023-03-10 CN disclosed
CN-112375048-B Method for preparing epoxide by promoting efficient epoxidation of diolefin and air under assistance of microwave 湖北大学 2022-11-18 CN disclosed
CN-108276376-B Novel diphenylpropenes derivative, preparation method thereof and pharmaceutical composition 北京理工大学 2020-06-05 CN disclosed
CN-110143910-A A kind of preparation method of polysubstituted pyrrole alkanone derivative 华侨大学 2019-08-20 CN disclosed
CN-1513027-A Styrenic thermoplastic resin composition LG化学株式会社 2004-07-14 CN disclosed
EP-1155093-B1 POLYURETHANE SEALANT COMPOSITIONS ESSEX SPECIALTY PROD (US) 2004-04-21 EP disclosed
US-6512033-B1 A urethane prepolymer having an isocyante functionality weight average molecular weight of at a catalytic amount of a tin compound which catalyzes the reaction of isocyanate moieties with water or an active a stabilizing amount of an ESSEX SPECIALTY PRODUCTS INC. 2003-01-28 US disclosed
EP-1155093-A1 POLYURETHANE SEALANT COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 2001-11-21 EP disclosed
WO-2000046320-A1 POLYURETHANE SEALANT COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 2000-08-10 WO disclosed
CN-1196069-A Phenolic polymers made by aralkylation reactions GEORGIA PACIFIC RESINS (US) 1998-10-14 CN disclosed
US-4480142-A USING ACID-TREATED CLAYS OR BORON TRIFLUORIDE-PHOSPHORIC ACID PHILLIPS PETROLEUM COMPANY (US) 1984-10-30 US disclosed