Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975491 | 0.82 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL10143912 | 0.81 | SMN1; SMN2 (1.00) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL2751880 | 0.81 | RAB9A (0.97) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL23457316 | 0.81 | SMN1; SMN2 (0.69) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL6422898 | 0.79 | HSD17B10 (0.62) | NPC1RAB9ASMN1; SMN2HPGDNPSR1 | |
| SCHEMBL23456441 | 0.78 | RAB9A (0.91) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL7299077 | 0.76 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL11526598 | 0.74 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL13302660 | 0.74 | NPSR1 (0.57) | SMN1; SMN2NPSR1POLBPKMMEN1 | |
| SCHEMBL8397397 | 0.74 | HSD17B10 (0.56) | NPC1RAB9ASMN1; SMN2HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960459-B2 | Curable composition | KANEKA CORPORATION (JP) | 2011-06-14 | — | — | US | disclosed |
| EP-1990371-B1 | CURABLE COMPOSITION | KANEKA CORP (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-20090186993-A1 | CURABLE COMPOSITION | KANEKA CORPORATION (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-1990371-A1 | CURABLE COMPOSITION | Kaneka Corporation (JP) | 2008-11-12 | — | — | EP | disclosed |