Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | FER | P16591 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526598 | 0.98 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL12327882 | 0.94 | HPGD (0.55) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL19251329 | 0.90 | NPSR1 (0.50) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL3427795 | 0.86 | KDM4E (0.49) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3768702 | 0.84 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL178394 | 0.82 | MAPK1 (0.47) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL28645971 | 0.82 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL8989433 | 0.82 | HTR6 (0.53) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL22399066 | 0.82 | HPGD (0.48) | NPC1RAB9ASMN1; SMN2HPGDALOX12 | |
| SCHEMBL19249016 | 0.82 | HPGD (0.48) | NPC1RAB9ASMN1; SMN2HPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300688-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | FISONS plc (GB) | 1989-01-25 | — | — | EP | claimed |
| US-20180118704-A1 | COMPOUNDS FOR TREATING PARASITIC INFECTIONS | UNIVERSITY OF MARYLAND, COLLEGE PARK | 2018-05-03 | — | — | US | disclosed |
| US-4582897-A | 2-AZO-4-SULFO-4-METHYLDIPHENYL SULFONE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0042357-B1 | AZO DYES, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1984-06-06 | — | — | EP | disclosed |
| US-4160643-A | FOR POLYMERS OF ACRYLONITRILE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-07-10 | — | — | US | disclosed |
| US-4067903-A | Manufacture of arylamines | BASF AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118704-A1 | COMPOUNDS FOR TREATING PARASITIC INFECTIONS | CYC1, COX15, SLC40A1 | NPC1 210/4885RAB9A 1985/4885SMN1; SMN2 4525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.