Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELE | P16581 | 13/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | SELL | P14151 | 2/20 | 0.31 |
| ▸ | SELP | P16109 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15070071 | 0.88 | SELE (0.58) | SELEALDH1A1THRBSLC5A1SLC5A2 | |
| SCHEMBL15070101 | 0.74 | SELE (0.49) | SELEALDH1A1THRBSLC5A1SLC5A2 | |
| SCHEMBL16661825 | 0.72 | SELE (0.54) | SELESELLSELP | |
| SCHEMBL19992328 | 0.72 | ALDH1A1 (0.38) | SELEALDH1A1THRB | |
| SCHEMBL17148758 | 0.71 | SELE (0.65) | SELESELL | |
| SCHEMBL19865609 | 0.71 | ALDH1A1 (0.38) | SELEALDH1A1THRB | |
| SCHEMBL19491946 | 0.71 | SELE (0.50) | SELEALDH1A1THRBSELP | |
| SCHEMBL17881698 | 0.70 | SELE (0.70) | SELE | |
| SCHEMBL15070099 | 0.70 | SELE (0.70) | SELE | |
| SCHEMBL16659815 | 0.70 | SELE (0.70) | SELE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296310-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GlycoMimetics, Inc. (US) | 2018-03-21 | — | — | EP | disclosed |