Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20793497 | 0.92 | TSHR (0.35) | TSHRCYP1A2USP2HIF1ACYP2D6 | |
| SCHEMBL20793504 | 0.92 | ITGB3 (0.39) | TSHRCYP1A2USP2CYP2D6CYP3A4 | |
| SCHEMBL20793670 | 0.92 | HRH3 (0.36) | TSHRCYP1A2USP2HIF1ACYP2D6 | |
| SCHEMBL19992846 | 0.92 | ITGB3 (0.36) | TSHRCYP1A2USP2HIF1ACYP2D6 | |
| SCHEMBL20793672 | 0.90 | HRH3 (0.38) | TSHRCYP1A2USP2HIF1ACYP2D6 | |
| SCHEMBL19992739 | 0.90 | ITGB3 (0.40) | TSHRCYP1A2USP2HIF1ACYP2D6 | |
| SCHEMBL23968808 | 0.79 | ITGB3 (0.37) | TSHRCYP1A2USP2HIF1ACYP2D6 | |
| SCHEMBL19083195 | 0.79 | CYP1A2 (0.34) | TSHRCYP1A2USP2HIF1ACYP2D6 | |
| SCHEMBL14671193 | 0.79 | ITGB3 (0.42) | TSHRCYP2D6CYP3A4ITGB3ITGA2B | |
| SCHEMBL19992729 | 0.78 | HSD17B10 (0.40) | TSHRCYP1A2USP2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053447-A1 | PIPERAZINE CARBAMATES AND METHODS OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |