Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15368000 | 0.81 | ATM (0.43) | ATMRAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL171892 | 0.75 | — | — | |
| SCHEMBL4826043 | 0.74 | — | — | |
| SCHEMBL13113182 | 0.72 | RAB9A (0.54) | ATMRAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL146803 | 0.71 | — | — | |
| SCHEMBL146802 | 0.71 | — | — | |
| SCHEMBL4109619 | 0.70 | ATM (0.58) | ATMRAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL5092259 | 0.69 | ESR1 (0.46) | ATMRAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL19930552 | 0.69 | NUDT1 (0.47) | ATMRAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL19736599 | 0.69 | ATM (0.39) | ATMRAB9ANPC1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927214-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |