Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | QDPR | P09417 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13599084 | 1.00 | NCF1 (0.36) | NCF1ALDH1A1CYP1A2TDP1HTT | |
| SCHEMBL19993130 | 0.91 | ALDH1A1 (0.40) | NCF1ALDH1A1HTTLMNA | |
| SCHEMBL20060186 | 0.81 | NCF1 (0.30) | NCF1 | |
| SCHEMBL4834075 | 0.78 | — | — | |
| SCHEMBL4834078 | 0.78 | — | — | |
| SCHEMBL27271798 | 0.78 | NCF1 (0.31) | NCF1 | |
| SCHEMBL17715546 | 0.76 | NCF1 (0.30) | NCF1 | |
| SCHEMBL12103422 | 0.76 | ALDH1A1 (0.39) | ALDH1A1CYP1A2TDP1HTTLMNA | |
| SCHEMBL22821268 | 0.75 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL15747136 | 0.73 | NCF1 (0.32) | NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927214-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |