SCHEMBL19993330

SCHEMBL19993330

Cc1ccc2cc(CCC3=C(F)CC(C)CC3)ccc2c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.36
CYP2A6 P11509 3/20 0.34
CYP1A2 P05177 2/20 0.34
HRH3 Q9Y5N1 3/20 0.33
ACHE P22303 1/20 0.33
LMNA P02545 2/20 0.32
TDP1 Q9NUW8 1/20 0.31
MAPT P10636 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21115686 0.76
SCHEMBL20813897 0.70
SCHEMBL24828784 0.66 CYP2A6 (0.45) CYP2A6CYP1A2LMNATDP1KCNH2
SCHEMBL3677920 0.64 CYP2A6 (0.56) CYP2A6CYP1A2TDP1
SCHEMBL18627004 0.64 KDM4E (0.46) CYP2A6CYP1A2LMNATDP1
SCHEMBL18745591 0.64 ALOX5 (0.40) CYP2A6CYP1A2HRH3ACHETDP1
SCHEMBL18594794 0.64 CYP2A6 (0.38) CYP2A6CYP1A2HRH3ACHELMNA
SCHEMBL12628596 0.63 CYP2A6 (0.54) CYP2A6CYP1A2LMNATDP1MAPT
SCHEMBL17208904 0.62 CYP2A6 (0.48) CYP2A6CYP1A2TDP1MAPTKCNH2
SCHEMBL3403193 0.62 CYP2A6 (0.52) CYP2A6CYP1A2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019030150-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE MERCK PATENT GMBH (DE) 2019-02-14 WO disclosed
WO-2019030153-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE MERCK PATENT GMBH (DE) 2019-02-14 WO disclosed
WO-2018104279-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE MERCK PATENT GMBH (DE) 2018-06-14 WO disclosed
WO-2018050573-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE MERCK PATENT GMBH (DE) 2018-03-22 WO disclosed