Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19993497 | 0.80 | HDAC8 (0.39) | MAPT | |
| SCHEMBL19087174 | 0.78 | — | — | |
| SCHEMBL19993538 | 0.75 | MAPK14 (0.34) | — | |
| SCHEMBL12824890 | 0.73 | PRSS1 (0.64) | PRSS1PRSS2PRSS3LMNAGFER | |
| SCHEMBL19993495 | 0.72 | NNMT (0.37) | LMNAL3MBTL1MAPTTDP1 | |
| SCHEMBL26311730 | 0.72 | PRSS1 (0.34) | PRSS1PRSS2PRSS3 | |
| SCHEMBL19993530 | 0.71 | MAPK14 (0.49) | — | |
| SCHEMBL25085750 | 0.69 | TDP1 (0.40) | KMT2ATDP1 | |
| SCHEMBL13636369 | 0.69 | TDP1 (0.61) | PRSS1PRSS2PRSS3LMNAGFER | |
| SCHEMBL23592021 | 0.69 | TSHR (0.50) | PRSS1PRSS2PRSS3LMNAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018052772-A1 | HETEROARYL CARBOXAMIDE COMPOUNDS AS INHIBITORS OF RIPK2 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-03-22 | — | — | WO | disclosed |