Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2001186 | 0.83 | RORC (0.44) | SCN9ACNR2TRPV3HDAC4MAPT | |
| SCHEMBL1995266 | 0.83 | DGAT2 (0.33) | HIF1AEPAS1GAAMAPTSMN1; SMN2 | |
| SCHEMBL2001814 | 0.82 | CNR1 (0.40) | CNR2HDAC4HIF1AEPAS1CNR1 | |
| SCHEMBL2008902 | 0.82 | CPT1A (0.35) | HIF1AEPAS1ALDH1A1GAAMAPT | |
| SCHEMBL1999329 | 0.82 | RORC (0.36) | HIF1AEPAS1 | |
| SCHEMBL2002698 | 0.81 | HIF1A (0.34) | CNR2HIF1AEPAS1ALDH1A1GAA | |
| SCHEMBL2005665 | 0.81 | HTT (0.37) | CNR2HDAC4HIF1AEPAS1CNR1 | |
| SCHEMBL2008087 | 0.80 | HDAC4 (0.45) | HDAC4HIF1AEPAS1ALDH1A1GAA | |
| SCHEMBL2000002 | 0.79 | HPGD (0.47) | SCN9ACNR2CNR1ALDH1A1POLB | |
| SCHEMBL2002907 | 0.79 | HDAC4 (0.44) | HDAC4HIF1AEPAS1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960377-B2 | Substituted pyridoxazines | CARA THERAPEUTICS, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| US-20090247502-A1 | SUBSTITUTED PYRIDOXAZINES | CARA THERAPEUTICS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247502-A1 | SUBSTITUTED PYRIDOXAZINES | CNR1, CNR2, TRPV1 | SCN9A 2158/4885CNR2 2/4885TRPV3 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.