Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994311 | 0.84 | NFE2L2 (0.35) | NFE2L2CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL9052646 | 0.81 | GSK3A (0.46) | NFE2L2GSK3AGSK3BMGLL | |
| SCHEMBL15352598 | 0.80 | JAK2 (0.43) | NFE2L2GSK3AGSK3BJAK2BTK | |
| SCHEMBL15352221 | 0.79 | GSK3A (0.36) | NFE2L2GSK3AGSK3BJAK2BTK | |
| SCHEMBL18500774 | 0.79 | GSK3A (0.36) | NFE2L2GSK3AGSK3BJAK2BTK | |
| SCHEMBL16425570 | 0.77 | GSK3A (0.34) | GSK3AGSK3BJAK2BTKMGLL | |
| SCHEMBL9051471 | 0.75 | MEN1 (0.39) | NFE2L2KDM4EMEN1LMNAPABPC1 | |
| SCHEMBL31398206 | 0.74 | GSK3A (0.33) | GSK3AGSK3B | |
| SCHEMBL18546293 | 0.74 | HCAR1 (0.42) | NFE2L2GSK3AGSK3BMEN1LMNA | |
| SCHEMBL20001772 | 0.73 | CYP2A6 (0.33) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018114541-A2 | MICROBIOCIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-28 | — | — | WO | disclosed |
| WO-2018055133-A1 | MICROBIOCIDAL TETRAZOLONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-29 | — | — | WO | disclosed |