Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994626 | 1.00 | MAOB (0.61) | MAOBMAOACCR2LMNAMAPT | |
| SCHEMBL27399824 | 0.87 | MAOB (0.57) | MAOBMAOACCR2LMNAHPGD | |
| SCHEMBL31556553 | 0.87 | MAOB (0.57) | MAOBMAOACCR2LMNAHPGD | |
| SCHEMBL27399822 | 0.87 | MAOB (0.57) | MAOBMAOACCR2LMNAHPGD | |
| SCHEMBL19994579 | 0.84 | MAOB (0.57) | MAOBMAOALMNANOTUMHPGD | |
| SCHEMBL19994578 | 0.84 | MAOB (0.57) | MAOBMAOALMNANOTUMHPGD | |
| SCHEMBL30836010 | 0.84 | MAOB (0.57) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL20015393 | 0.84 | MAOB (0.57) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL20015408 | 0.84 | MAOB (0.57) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL19994618 | 0.83 | MAOB (0.58) | MAOBMAOAMAPTNPSR1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426634-A1 | DISUBTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES AS INHIBITORS OF MONOAMINE OXIDASE B FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | University of Ljubljana (SI) | 2019-01-16 | — | — | EP | disclosed |
| WO-2018055096-A1 | DISUBTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES AS INHIBITORS OF MONOAMINE OXIDASE B FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIVERSITY OF LJUBLJANA (SI) | 2018-03-29 | — | — | WO | disclosed |