SCHEMBL30836010

SCHEMBL30836010

CC(C)(C)OC(=O)N1CCC(C=Cc2cccc(C(F)(F)F)c2)CC1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.57
MAOA P21397 1/20 0.57
STS P08842 1/20 0.47
GPR119 Q8TDV5 9/20 0.47
TGFBR1 P36897 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
MAPT P10636 2/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20015393 1.00 MAOB (0.57) MAOBMAOASTSGPR119TGFBR1
SCHEMBL20015408 1.00 MAOB (0.57) MAOBMAOASTSGPR119TGFBR1
SCHEMBL31556551 0.94 MAOB (0.53) MAOBMAOASTSGPR119TGFBR1
SCHEMBL14261777 0.91 GPR119 (0.47) MAOBMAOASTSGPR119TGFBR1
SCHEMBL27401519 0.89 MAOB (0.48) MAOBMAOAGPR119MEN1KMT2A
SCHEMBL14261782 0.87 MAOA (0.54) MAOBMAOASTSGPR119MEN1
SCHEMBL6011915 0.87 GPR119 (0.47) MAOBMAOASTSGPR119MAPT
SCHEMBL20015327 0.87 MAOA (0.54) MAOBMAOASTSGPR119MEN1
SCHEMBL14261790 0.86 MAOB (0.54) MAOBSTSGPR119TGFBR1MEN1
SCHEMBL21381646 0.86 MAOB (0.54) MAOBSTSGPR119TGFBR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4587424-A1 YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS Bridgene Biosciences, Inc. (US) 2025-07-23 EP disclosed
WO-2024059317-A1 YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS BRIDGENE BIOSCIENCES, INC. (US) 2024-03-21 WO disclosed