Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL27480269 | 1.00 | ALDH1A1 (0.63) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL27891121 | 0.91 | ALDH1A1 (0.52) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| SCHEMBL27753337 | 0.88 | ALDH1A1 (0.43) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL27548983 | 0.85 | ALDH1A1 (0.46) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoxaline SCHEMBL27493680 | 0.84 | ALDH1A1 (0.38) | ALDH1A1NPC1POLBRAB9AKDM4E | |
| Phenazine SCHEMBL27734838 | 0.82 | MAPT (0.50) | ALDH1A1NPC1POLBRAB9AKDM4E | |
| Naphthalene SCHEMBL27805984 | 0.82 | CYP2A6 (0.40) | ALDH1A1CYP2A6 | |
| Quinoline SCHEMBL27641019 | 0.82 | ALDH1A1 (0.94) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| SCHEMBL4882550 | 0.81 | ALDH1A1 (0.39) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Cinnoline SCHEMBL27939099 | 0.80 | ALDH1A1 (0.36) | ALDH1A1NPC1RAB9ACYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210361642-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | BAR ILAN UNIVERSITY (IL) | 2021-11-25 | — | — | US | claimed |
| EP-3515435-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | Bar-Ilan University (IL) | 2019-07-31 | — | — | EP | claimed |
| CN-108713025-A | Slave single carrier for treating the heart patient's condition and other pathology expresses the composition and method of multiple biological activities polypeptide | 英特拉克森公司 | 2018-10-26 | — | — | CN | claimed |
| WO-2018055627-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | BAR ILAN UNIVERSITY (IL) | 2018-03-29 | — | — | WO | claimed |
| CN-106986926-A | The mutain and its preparation method of tear lipocalin with the compatibility to people's C MET receptor tyrosine kinases | 皮里斯股份公司 | 2017-07-28 | — | — | CN | claimed |
| CN-104994851-A | PYRAZOLYL-BASED CARBOXAMIDES I AS CRAC CHANNEL INHIBITORS | GRUENENTHAL CHEMIE | 2015-10-21 | — | — | CN | claimed |
| CN-101883845-B | Engineered dendritic cells and uses for the treatment of cancer | INTREXON CORP | 2015-06-10 | — | — | CN | claimed |
| CN-103534355-A | Vectors conditionally expressing protein | INTREXON CORP | 2014-01-22 | — | — | CN | claimed |
| CN-101421225-B | Aromatic amine derivative and organic electroluminescent element using same | IDEMITSU KOSAN CO | 2013-11-06 | — | — | CN | claimed |
| CN-102241719-A | Glycopyrrolate compounds and synthesis method thereof | UNIV DALIAN TECH | 2011-11-16 | — | — | CN | claimed |
| CN-1678192-A | Arthropodicidal anthranilamides | DU PONT (US) | 2005-10-05 | — | — | CN | claimed |
| CN-1556806-A | Arthropodicidal anthranilamides | �Ű˾ | 2004-12-22 | — | — | CN | claimed |
| CN-1555364-A | Insecticidal diamides | �Ű˾ | 2004-12-15 | — | — | CN | claimed |
| CN-1541063-A | Method for controlling particular insects by applying anthranilamide compounds | ��Ļ���Ű˾ | 2004-10-27 | — | — | CN | claimed |
| CN-1530371-A | Fructose spiro-compound with anti-cancer activity | 北京大学 | 2004-09-22 | — | — | CN | claimed |
| CN-1426392-A | Propenecarboxylic acid amidoxime derivatives, process for their preparation and pharmaceutical compositions containing them | GENE RES LAB CO N (US) | 2003-06-25 | — | — | CN | claimed |
| CN-1369573-A | deposition apparatus and deposition method | SEMICONDUCTOR ENERGY LAB (JP) | 2002-09-18 | — | — | CN | claimed |
| CN-1003627-B | solid pesticide composition | 组合化学工业株式会社 | 1989-03-22 | — | — | CN | claimed |
| CN-87102972-A | Treatment senile dementia oxadiazoles useful | — | 1987-11-18 | — | — | CN | claimed |
| CN-85108655-A | SOLID FARM CHEMICAL COMPOUND | — | 1986-09-10 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210361642-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | XIAP, BRWD1, ZAP70 | ALDH1A1 4585/4885NPC1 2333/4885POLB 1839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.