Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoxaline SCHEMBL27493680 | 0.91 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| Quinoline SCHEMBL19995127 | 0.88 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| Quinoline SCHEMBL27480269 | 0.88 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| Oxazole SCHEMBL27681784 | 0.86 | ALDH1A1 (0.33) | ALDH1A1MAPTKDM4E | |
| Phenazine SCHEMBL27734838 | 0.80 | MAPT (0.50) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| SCHEMBL26099015 | 0.79 | — | — | |
| SCHEMBL4882550 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| Dipyridyl SCHEMBL2946110 | 0.77 | KDM4E (0.58) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| Benzene SCHEMBL27338794 | 0.75 | PARP1 (0.33) | — | |
| SCHEMBL8194 | 0.75 | ALDH1A1 (0.67) | ALDH1A1MAPTKDM4EPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279841-A | Photocurable adhesion promoting compositions and methods of use thereof | PRC-迪索托国际公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-102292338-A | Tyrosine kinase protein receptor antagonists | — | 2011-12-21 | — | — | CN | disclosed |
| CN-102177153-A | Pharmaceutical combinations and methods for treating alcohol use disorders, pain and other diseases | VM DISCOVERY INC | 2011-09-07 | — | — | CN | disclosed |
| CN-102164905-A | Compounds, compositions, and uses thereof as hypoxia mimetics | BEIJING BETA PHARMA INC | 2011-08-24 | — | — | CN | disclosed |
| CN-1625400-B | 2, 4-pyrimidinediamine compounds and uses thereof | RIGEL PHARMACEUTICALS INC | 2011-04-13 | — | — | CN | disclosed |
| CN-101778563-A | Compositions and methods for apoptosis modulators | VM DISCOVERY INC | 2010-07-14 | — | — | CN | disclosed |
| CN-101490551-A | Methods of analyzing binding interactions | APPLERA CORP (US) | 2009-07-22 | — | — | CN | disclosed |