Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19995460 | 0.87 | KMT2A (0.70) | TSHRALDH1A1POLBL3MBTL1MAPT | |
| SCHEMBL20011475 | 0.87 | HPGD (0.78) | TSHRALDH1A1POLBLMNARAB9A | |
| SCHEMBL5711647 | 0.80 | ALDH1A1 (0.78) | TSHRALDH1A1POLBLMNARAB9A | |
| SCHEMBL5480773 | 0.80 | ALDH1A1 (0.78) | TSHRALDH1A1POLBLMNARAB9A | |
| SCHEMBL20011254 | 0.78 | ALDH1A1 (0.64) | ALDH1A1POLBRAB9AHPGDL3MBTL1 | |
| SCHEMBL18556531 | 0.77 | POLB (0.81) | TSHRALDH1A1POLBLMNARAB9A | |
| SCHEMBL18556533 | 0.77 | TSHR (1.00) | TSHRALDH1A1POLBLMNARAB9A | |
| SCHEMBL18556537 | 0.76 | ALDH1A1 (1.00) | TSHRALDH1A1POLBLMNARAB9A | |
| SCHEMBL15983469 | 0.76 | POLB (1.00) | TSHRALDH1A1POLBLMNARAB9A | |
| SCHEMBL18556573 | 0.75 | HPGD (1.00) | TSHRALDH1A1HPGDKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515435-B1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | UNIV BAR ILAN (IL) | 2026-02-25 | — | — | EP | claimed |
| US-11123339-B2 | WASp-protecting small molecules, compositions, methods and uses thereof in the treatment of innate and acquired immune-related disorders or conditions | BAR ILAN UNIVERSITY (IL) | 2021-09-21 | — | — | US | claimed |
| EP-3515435-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | Bar-Ilan University (IL) | 2019-07-31 | — | — | EP | claimed |
| US-20190216794-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | BAR ILAN UNIVERSITY (IL) | 2019-07-18 | — | — | US | claimed |
| WO-2018055627-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | BAR ILAN UNIVERSITY (IL) | 2018-03-29 | — | — | WO | claimed |
| EP-3515435-B1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | UNIV BAR ILAN (IL) | 2026-02-25 | — | — | EP | disclosed |
| US-12150940-B2 | WASp-protecting small molecules, compositions, methods and uses thereof in the treatment of innate and acquired immune-related disorders or conditions | BAR ILAN UNIVERSITY (IL) | 2024-11-26 | — | — | US | disclosed |
| US-20210361642-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | BAR ILAN UNIVERSITY (IL) | 2021-11-25 | — | — | US | disclosed |
| US-20210361642-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | BAR ILAN UNIVERSITY (IL) | 2021-11-25 | — | — | US | disclosed |
| US-11123339-B2 | WASp-protecting small molecules, compositions, methods and uses thereof in the treatment of innate and acquired immune-related disorders or conditions | BAR ILAN UNIVERSITY (IL) | 2021-09-21 | — | — | US | disclosed |
| US-11123339-B2 | WASp-protecting small molecules, compositions, methods and uses thereof in the treatment of innate and acquired immune-related disorders or conditions | BAR ILAN UNIVERSITY (IL) | 2021-09-21 | — | — | US | disclosed |
| EP-3515435-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | Bar-Ilan University (IL) | 2019-07-31 | — | — | EP | disclosed |
| US-20190216794-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | BAR ILAN UNIVERSITY (IL) | 2019-07-18 | — | — | US | disclosed |
| US-20190216794-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | BAR ILAN UNIVERSITY (IL) | 2019-07-18 | — | — | US | disclosed |
| WO-2018055627-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | BAR ILAN UNIVERSITY (IL) | 2018-03-29 | — | — | WO | disclosed |
| WO-2018055627-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | BAR ILAN UNIVERSITY (IL) | 2018-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12150940-B2 | WASp-protecting small molecules, compositions, methods and uses thereof in the treatment of innate and acquired immune-related disorders or conditions | XIAP, BRWD1, ZAP70 | TSHR 4666/4885ALDH1A1 4585/4885POLB 1839/4885 |
| US-20210361642-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | XIAP, BRWD1, ZAP70 | TSHR 4666/4885ALDH1A1 4585/4885POLB 1839/4885 |
| US-11123339-B2 | WASp-protecting small molecules, compositions, methods and uses thereof in the treatment of innate and acquired immune-related disorders or conditions | XIAP, BRWD1, ZAP70 | TSHR 4666/4885ALDH1A1 4585/4885POLB 1839/4885 |
| US-20190216794-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | XIAP, BRWD1, ZAP70 | TSHR 4666/4885ALDH1A1 4585/4885POLB 1839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.