Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA7 | P43166 | 4/20 | 0.56 |
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3530288 | 0.98 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL26162772 | 0.92 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1999536 | 0.92 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17344113 | 0.88 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9034755 | 0.84 | MAPK1 (0.48) | MAPK1CYP3A4NPSR1KDM4EALDH1A1 | |
| SCHEMBL10479256 | 0.82 | MAPK1 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14653302 | 0.82 | SMN1; SMN2 (0.49) | MAPK1CYP3A4NPSR1KDM4EALDH1A1 | |
| SCHEMBL13936781 | 0.82 | CA12 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21044559 | 0.81 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21200395 | 0.80 | POLB (0.42) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250339570-A1 | RADIOIMMUNOCONJUGATES AND THERAPEUTIC USES THEREOF | UNIV CALIFORNIA (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250214985-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | CORNELL UNIVERSITY (US) | 2025-07-03 | — | — | US | disclosed |
| US-20250163040-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | CORNELL UNIVERSITY (US) | 2025-05-22 | — | — | US | disclosed |
| EP-4525939-A2 | RADIOIMMUNOCONJUGATES AND THERAPEUTIC USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-03-26 | — | — | EP | disclosed |
| US-12258339-B2 | Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer | CORNELL UNIVERSITY (US) | 2025-03-25 | — | — | US | disclosed |
| WO-2025031383-A1 | BIFUNCTIONAL LINKER COMPOUND, ANTIBODY DRUG CONJUGATE, PREPARATION METHOD FOR ANTIBODY DRUG CONJUGATE, AND USE OF ANTIBODY DRUG CONJUGATE | 杭州爱科瑞思生物医药有限公司 | 2025-02-13 | — | — | WO | disclosed |
| US-12103922-B2 | Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer | CORNELL UNIVERSITY (US) | 2024-10-01 | — | — | US | disclosed |
| US-20240254085-A1 | CHELATORS FOR RADIOMETALS AND METHODS OF MAKING AND USING SAME | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-08-01 | — | — | US | disclosed |
| EP-4334290-A1 | CHELATORS FOR RADIOMETALS AND METHODS OF MAKING AND USING SAME | The University of British Columbia (CA) | 2024-03-13 | — | — | EP | disclosed |
| US-11840521-B2 | Modulators of Mas-related G-protein receptor X4 and related products and methods | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| US-20100134052-A1 | Light Emitting Polymer Devices Using Self-Assembled Monolayer Structures | HCF PARTNERS, L.P. (US) | 2010-06-03 | — | — | US | disclosed |
| US-20100134052-A1 | Light Emitting Polymer Devices Using Self-Assembled Monolayer Structures | HCF PARTNERS, L.P. (US) | 2010-06-03 | — | — | US | disclosed |
| US-20090149470-A1 | Novel aminopyridine derivatives having aurora a selective inhibitory action | MSD K.K. (JP) | 2009-06-11 | — | — | US | disclosed |
| US-20090149470-A1 | Novel aminopyridine derivatives having aurora a selective inhibitory action | MSD K.K. (JP) | 2009-06-11 | — | — | US | disclosed |
| US-7491720-B2 | Aminopyridine derivatives having Aurora A selective inhibitory action | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-02-17 | — | — | US | disclosed |
| US-7491720-B2 | Aminopyridine derivatives having Aurora A selective inhibitory action | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-02-17 | — | — | US | disclosed |
| WO-2008034911-A1 | NEW BIO-COMPATIBLE POLYMER MATERIALS, METHOD FOR PRODUCING THE SAME AND USES THEREOF, PARTICULARLY IN MEDICAL MAGNETIC-RESONANCE IMAGING | BIOSPHERE MEDICAL (FR) | 2008-03-27 | — | — | WO | disclosed |
| US-20080027042-A1 | Novel Aminopyridine Derivatives Having Aurora a Selective Inhibitory Action | OHKUBO MITSURU | 2008-01-31 | — | — | US | disclosed |
| US-20080027042-A1 | Novel Aminopyridine Derivatives Having Aurora a Selective Inhibitory Action | OHKUBO MITSURU | 2008-01-31 | — | — | US | disclosed |
| WO-2006116584-A2 | LIGHT EMITTING POLYMER DEVICES USING SELF-ASSEMBLED MONOLAYER STRUCTURES | DYNAMIC ORGANIC LIGHT, INC. (US) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11840521-B2 | Modulators of Mas-related G-protein receptor X4 and related products and methods | MRGPRX4, MRGPRX1, MRGPRX2 | CA12 2960/4885CA1 2436/4885CA2 1316/4885 |
| US-20250339570-A1 | RADIOIMMUNOCONJUGATES AND THERAPEUTIC USES THEREOF | ITGA6, CD4, ITGB6 | CA12 68/4885CA1 173/4885CA2 1280/4885 |
| US-20080027042-A1 | Novel Aminopyridine Derivatives Having Aurora a Selective Inhibitory Action | AURKA, AURKC, AURKB | CA12 2178/4885CA1 536/4885CA2 190/4885 |
| US-20090149470-A1 | Novel aminopyridine derivatives having aurora a selective inhibitory action | AURKA, AURKC, AURKB | CA12 2178/4885CA1 536/4885CA2 190/4885 |
| US-20250163040-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | PSMA1, FOLH1, KLK3 | CA12 22/4885CA1 50/4885CA2 420/4885 |
| US-20100134052-A1 | Light Emitting Polymer Devices Using Self-Assembled Monolayer Structures | CLTB, CYBA, CLTA | CA12 2379/4885CA1 3166/4885CA2 4510/4885 |
| US-12258339-B2 | Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer | PSMA1, FOLH1, KLK3 | CA12 22/4885CA1 50/4885CA2 420/4885 |
| US-12103922-B2 | Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer | PSMA1, KLK3, FOLH1 | CA12 24/4885CA1 59/4885CA2 308/4885 |
| US-20250214985-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | PSMA1, FOLH1, KLK3 | CA12 22/4885CA1 50/4885CA2 420/4885 |
| US-20240254085-A1 | CHELATORS FOR RADIOMETALS AND METHODS OF MAKING AND USING SAME | RXFP3, SLC39A3, NR4A3 | CA12 618/4885CA1 439/4885CA2 2392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.