Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL2771650 | 1.00 | CA2 (0.50) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL21184393 | 1.00 | CA2 (0.50) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL21184392 | 1.00 | CA2 (0.50) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL2771652 | 1.00 | CA2 (0.50) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL28910806 | 0.95 | CA2 (0.46) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL14856512 | 0.95 | CA2 (0.46) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL28832415 | 0.95 | CA2 (0.46) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL9779888 | 0.95 | CA2 (0.46) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL27378145 | 0.95 | CA2 (0.46) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL7565065 | 0.95 | CA2 (0.46) | CA2CA1CA9BLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107438615-A | For preparing the method and kit of radionuclide complex compound | 施拉格诺斯迪克斯有限公司 | 2017-12-05 | — | — | CN | disclosed |
| CN-105579503-A | Polyolefin compositions for building materials | BASF SE | 2016-05-11 | — | — | CN | disclosed |
| CN-103339172-A | Methods of flame retarding polyethylene processed at high temperatures | BASF SE | 2013-10-02 | — | — | CN | disclosed |
| US-7959682-B2 | highly biocompatible, nontoxic, biodegrabable, cause no immunological or irritating response, have excellent osteoconductivity; comprising a mixture of at least a skeleton substance and at least one functional substance | ADC Advanced Dental Care GmbH & Co. KG (DE) | 2011-06-14 | — | — | US | disclosed |
| US-20050163861-A1 | Method for producing bone substitution material | ADC ADVANCED DENTAL CRE GMBH & CO KG | 2005-07-28 | — | — | US | disclosed |
| EP-1520593-A1 | Method for producing bone substitution material | ADC Advanced Dental Care GmbH & CO KG (DE) | 2005-04-06 | — | — | EP | disclosed |
| EP-0211797-B1 | IMPROVED BORON PHOSPHATE CATALYST FOR THE PRODUCTION OF DIENES FROM ALDEHYDES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-03-01 | — | — | EP | disclosed |
| EP-0211797-A1 | Improved boron phosphate catalyst for the production of dienes from aldehydes | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-02-25 | — | — | EP | disclosed |
| US-4632913-A | AMMONIUM CARBONATE MODIFIED CATALYST, CALCINED FOR LARGE PORE SIZE; ISOPRENE PRODUCTION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-12-30 | — | — | US | disclosed |
| US-4587372-A | DEHYDRATION CATALYSTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-05-06 | — | — | US | disclosed |