Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17949310 | 0.94 | SPR (0.36) | SPRTRPV1RORCSCN10ANAMPT | |
| SCHEMBL19996416 | 0.92 | LMNA (0.34) | SPRTRPV1RORCNAMPTGAA | |
| SCHEMBL19996410 | 0.88 | TRPV1 (0.38) | SPRTRPV1RORCNAMPTGAA | |
| SCHEMBL17949351 | 0.87 | TRPV1 (0.38) | SPRTRPV1RORCNAMPTGAA | |
| SCHEMBL17942440 | 0.87 | TRPV1 (0.36) | SPRTRPV1RORCSCN10ANAMPT | |
| SCHEMBL19996439 | 0.87 | TRPV1 (0.38) | SPRTRPV1RORCNAMPTGAA | |
| SCHEMBL17948928 | 0.86 | LMNA (0.35) | SPRTRPV1RORCNAMPTGAA | |
| SCHEMBL17949465 | 0.83 | TRPV1 (0.37) | SPRTRPV1RORCNAMPTGAA | |
| SCHEMBL29529794 | 0.83 | TRPV1 (0.37) | SPRTRPV1RORCNAMPTGAA | |
| SCHEMBL19996431 | 0.82 | CNR2 (0.35) | SPRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9925177-B2 | 4-methylsulfonyl-substituted piperidine urea compounds | MyoKardia, Inc. (US) | 2018-03-27 | — | — | US | disclosed |