Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | SLC22A4 | Q9H015 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17308656 | 0.88 | CYP2C19 (0.32) | POLBALPLALPG | |
| SCHEMBL19996547 | 0.88 | POLB (0.45) | POLBALPLALPGSLC22A4GAA | |
| SCHEMBL19996541 | 0.83 | POLB (0.49) | POLBALPLALPGSLC22A4GAA | |
| SCHEMBL19996546 | 0.83 | POLB (0.49) | POLBALPLALPGSLC22A4GAA | |
| SCHEMBL19996544 | 0.78 | POLB (0.46) | POLBALPLALPGSLC22A4GAA | |
| SCHEMBL17308681 | 0.75 | CYP2C19 (0.34) | POLBALPLALPGSLC22A4 | |
| SCHEMBL17308674 | 0.72 | CYP2C19 (0.32) | — | |
| SCHEMBL17308675 | 0.72 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL19085618 | 0.72 | CYP1A2 (0.33) | — | |
| SCHEMBL19499944 | 0.71 | POLB (0.45) | POLBALPLALPGSLC22A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926300-B2 | 5-acylsulfanyl-histidine compounds as precursors of the corresponding 5-sulfanylhistidines and their disulfides | TETRAHEDRON (FR) | 2018-03-27 | — | — | US | disclosed |
| US-9926300-B2 | 5-acylsulfanyl-histidine compounds as precursors of the corresponding 5-sulfanylhistidines and their disulfides | TETRAHEDRON (FR) | 2018-03-27 | — | — | US | disclosed |