Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SLC22A4 | Q9H015 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19996546 | 1.00 | POLB (0.49) | POLBALPLALPGGAASLC22A4 | |
| SCHEMBL17308677 | 0.91 | POLB (0.36) | POLBALPLALPGGAAALDH1A1 | |
| SCHEMBL17308620 | 0.91 | POLB (0.36) | POLBALPLALPGGAAALDH1A1 | |
| SCHEMBL19996539 | 0.83 | POLB (0.42) | POLBALPLALPGGAASLC22A4 | |
| SCHEMBL19996547 | 0.81 | POLB (0.45) | POLBALPLALPGGAASLC22A4 | |
| SCHEMBL17308623 | 0.77 | SLC7A5 (0.42) | ALDH1A1HPGDHTTRAB9ASMN1; SMN2 | |
| SCHEMBL19085686 | 0.76 | ALDH1A1 (0.34) | GAAALDH1A1HPGDHTTRAB9A | |
| SCHEMBL17308656 | 0.74 | CYP2C19 (0.32) | POLBALPLALPG | |
| SCHEMBL17308681 | 0.72 | CYP2C19 (0.34) | POLBALPLALPGSLC22A4CYP1A2 | |
| SCHEMBL19996544 | 0.72 | POLB (0.46) | POLBALPLALPGGAASLC22A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926300-B2 | 5-acylsulfanyl-histidine compounds as precursors of the corresponding 5-sulfanylhistidines and their disulfides | TETRAHEDRON (FR) | 2018-03-27 | — | — | US | disclosed |