Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19996539 | 0.88 | POLB (0.42) | ALPLPOLBALPG | |
| SCHEMBL17308681 | 0.87 | CYP2C19 (0.34) | CYP2C19HSD17B10ALPLPOLBALPG | |
| SCHEMBL17308677 | 0.84 | POLB (0.36) | ALPLPOLBALPG | |
| SCHEMBL17308684 | 0.81 | SLC7A5 (0.43) | HSD17B10POLB | |
| SCHEMBL17293237 | 0.81 | SLC7A5 (0.43) | HSD17B10POLB | |
| SCHEMBL17308624 | 0.81 | SLC7A5 (0.43) | HSD17B10POLB | |
| SCHEMBL17308675 | 0.78 | SMN1; SMN2 (0.34) | CYP2C19HSD17B10 | |
| SCHEMBL17308674 | 0.78 | CYP2C19 (0.32) | CYP2C19HSD17B10 | |
| SCHEMBL19085618 | 0.78 | CYP1A2 (0.33) | CYP2C19HSD17B10 | |
| SCHEMBL19077817 | 0.77 | TNF (0.37) | CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926300-B2 | 5-acylsulfanyl-histidine compounds as precursors of the corresponding 5-sulfanylhistidines and their disulfides | TETRAHEDRON (FR) | 2018-03-27 | — | — | US | disclosed |
| US-20170190691-A1 | NOVEL 5-ACYLSULFANYL-HISTIDINE COMPOUNDS AS PRECURSORS OF THE CORRESPONDING 5-SULFANYLHISTIDINES AND THEIR DISULFIDES | TETRAHEDRON (FR) | 2017-07-06 | — | — | US | disclosed |
| WO-2015181507-A1 | NOVEL COMPOUNDS OF THE 5-ACYLSULFANYL-HISTIDINE TYPE AS PRECURSORS OF THE CORRESPONDING 5-SULFANYLHISTIDINES AND THE DISULFIDES THEREOF | TETRAHEDRON (FR) | 2015-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190691-A1 | NOVEL 5-ACYLSULFANYL-HISTIDINE COMPOUNDS AS PRECURSORS OF THE CORRESPONDING 5-SULFANYLHISTIDINES AND THEIR DISULFIDES | AHCYL1, CBS, H1-5 | CYP2C19 2240/4885HSD17B10 465/4885ALPL 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.