Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | PAM | P19021 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19996571 | 0.92 | ALDH1A1 (0.62) | ALDH1A1MAPK1L3MBTL1TDP1PAM | |
| SCHEMBL6943482 | 0.87 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL6943486 | 0.87 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL17084551 | 0.86 | TDP1 (0.67) | ALDH1A1MAPK1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL361779 | 0.86 | ALDH1A1 (1.00) | ALDH1A1MAPK1L3MBTL1TDP1PAM | |
| SCHEMBL18668857 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL18668855 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL16672454 | 0.85 | TDP1 (0.56) | ALDH1A1MAPK1L3MBTL1TDP1TSHR | |
| SCHEMBL18673 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL4570308 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1TDP1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9925521-B2 | Chromatographic materials | WATERS TECHNOLOGIES CORPORATION (US) | 2018-03-27 | — | — | US | disclosed |
| US-9925521-B2 | Chromatographic materials | WATERS TECHNOLOGIES CORPORATION (US) | 2018-03-27 | — | — | US | disclosed |