Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | PAM | P19021 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19996569 | 0.92 | ALDH1A1 (0.74) | ALDH1A1MAPK1L3MBTL1TDP1PAM | |
| SCHEMBL2652042 | 0.89 | ALDH1A1 (0.79) | ALDH1A1MAPK1L3MBTL1CYP19A1POLB | |
| SCHEMBL20224953 | 0.83 | POLB (0.52) | ALDH1A1MAPK1L3MBTL1POLBTDP1 | |
| SCHEMBL31692116 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1CYP19A1POLB | |
| SCHEMBL19996555 | 0.81 | ATM (0.58) | ALDH1A1MAPK1L3MBTL1CYP19A1POLB | |
| SCHEMBL20224987 | 0.80 | TDP1 (0.64) | ALDH1A1MAPK1L3MBTL1CYP19A1POLB | |
| SCHEMBL6943486 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1POLBTDP1 | |
| SCHEMBL6943482 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1TDP1LMNA | |
| SCHEMBL17084551 | 0.79 | TDP1 (0.67) | ALDH1A1MAPK1L3MBTL1TDP1LMNA | |
| SCHEMBL361779 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MAPK1L3MBTL1TDP1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9925521-B2 | Chromatographic materials | WATERS TECHNOLOGIES CORPORATION (US) | 2018-03-27 | — | — | US | disclosed |
| US-9925521-B2 | Chromatographic materials | WATERS TECHNOLOGIES CORPORATION (US) | 2018-03-27 | — | — | US | disclosed |